The side effects and relief methods of Japanese Ono Limaprost tablets
Limaprost tablets are a prostaglandin E1 derivative primarily used to improve peripheral circulation disorders. Its side effects are often related to vasodilation, and can be effectively controlled through rational medication and monitoring. The following is a detailed explanation of the side effects and countermeasures of the drug.
1. Common side effects and alleviation
(1) Digestive system response
Nausea, diarrhea, or stomach discomfort may occur, and it is recommended to take it after meals to alleviate symptoms. If it persists, consider reducing the dosage or administering it in divided doses.
(2) Skin flushing
About 15% of patients experience facial flushing, which is usually a temporary reaction. Keeping the environment cool can alleviate symptoms, and in severe cases, consult a doctor to adjust the dosage.
(3) Headache and dizziness
Related to vasodilation, it is recommended to avoid sudden standing up after taking medication. Those with obvious symptoms may consider taking medication at night to reduce discomfort.
2. Serious side effects to be wary of
(1) Low blood pressure risk
May cause a decrease in blood pressure, regular monitoring of blood pressure is necessary during medication. Elderly patients and the use of combination antihypertensive drugs should be particularly cautious.
(2) Bleeding tendency
May prolong bleeding time, medication history should be informed in advance before surgery. If abnormal bleeding occurs, seek medical attention immediately and have platelet function checked.
(3) Allergic reactions
Rare but may cause rash or difficulty breathing, immediate discontinuation of medication and receipt of anti allergic treatment is required. Patients with a history of allergies should use with caution.
3. Precautions for special populations
(1) Cardiovascular disease patients
Patients with heart failure should use it under close monitoring, and the initial dose should be halved. If palpitations or chest pain occur, stop medication immediately for evaluation.
(2) Liver and kidney dysfunction
Patients with moderate or severe liver and kidney dysfunction need to adjust their dosage. It is recommended to regularly check liver and kidney function indicators before and during treatment.
(3) Pregnancy and lactation period
Pregnant women are prohibited from using medication, and breastfeeding should be suspended during lactation. Women of childbearing age should take reliable contraceptive measures during medication.
4. Drug interaction management
(1) Antihypertensive drugs
Combined use with antihypertensive drugs may enhance the antihypertensive effect, and close monitoring of blood pressure changes is necessary. Adjust the dosage of antihypertensive drugs if necessary.
(2) Anticoagulant drugs
May enhance the effectiveness of anticoagulants such as warfarin, and increase the frequency of INR testing during combination use. Pay attention to the bleeding tendency.
(3) Non steroidal anti-inflammatory drugs
NSAIDs may weaken the efficacy of limaprost and long-term combination therapy should be avoided. If necessary, take it at least 4 hours apart.
Disclaimer：《The side effects and relief methods of Japanese Ono Limaprost tablets》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！