Side effects and mitigation methods of Cabergoline
The side effects of Cabergoline can be classified into severe reactions that require immediate medical attention, common reactions that may self resolve, and special behavioral abnormalities. Preventive measures include symptom recognition, dosage adjustment, and contraindication management.
1. Serious side effects requiring immediate medical attention
(1) Cardiovascular system: fainting, orthostatic hypotension (especially when the initial dose is>1mg), blood pressure should be monitored and rapid changes in posture should be avoided.
(2) Psychological symptoms: hallucinations (seeing/hearing non-existent things), aggressive behavior, or delusions of persecution, immediate discontinuation of medication is required.
(3) Fibrotic lesions: heart valve disease, pleural effusion or pulmonary fibrosis, long-term medication requires regular imaging examinations.
2. Common side effects that may self alleviate
(1) Digestive system: stomach pain, constipation, diarrhea, indigestion, usually relieved with prolonged medication.
(2) Nervous system: headache, dizziness, drowsiness, it is recommended to avoid driving or operating machinery.
(3) Other symptoms include nasal congestion, facial flushing, and joint pain, which can be relieved through symptomatic treatment.
3. Abnormal side effects of special behaviors
(1) Impulsive control disorder: pathological gambling, hypersexuality, binge eating, etc., can be reversed after reducing or stopping medication.
(2) Emotional changes: Depression, anxiety, or abnormal excitement require close monitoring of psychological status.
4. Prevention and mitigation measures for side effects
(1) Dose control: The initial low dose (0.25-0.5mg/week) is gradually adjusted to reduce cardiovascular risk.
(2) Taboo management: Pregnant women with hypertension are prohibited from using it, and strict contraception is required during medication.
(3) Monitoring requirements: Regular assessment of cardiac function, blood pressure, and psychiatric symptoms, especially for long-term users.
5. Excessive processing
(1) Symptomatic support: Maintain stable blood pressure, and use vasoconstrictors for severe nasal congestion.
(2) Clearance measures: Gastric lavage is ineffective (slow absorption), and continuous observation is required for 63-69 hours (half-life).
Disclaimer：《Side effects and mitigation methods of Cabergoline》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！