Indications, usage and dosage of Cabergoline
Cabergoline is a dopamine D2 receptor agonist mainly used to treat hyperprolactinemia and related diseases. Its dosage needs to be gradually adjusted according to prolactin levels, and potential risks such as fibrosis and hypotension should be monitored.
1. Indications
(1) Hyperprolactinemia: Suitable for the treatment of pituitary adenomas (prolactinomas) and idiopathic hyperprolactinemia, improving symptoms by inhibiting prolactin secretion.
2. Usage and dosage
(1) Initial dose: It is recommended to take 0.25mg orally twice a week, adjusted according to efficacy and tolerability.
(2) Dose adjustment: Gradually increase in increments of 0.25mg twice a week, with a minimum interval of 4 weeks between each increment, and the maximum dose should not exceed 1mg twice a week.
(3) Maintenance therapy: Regular monitoring of prolactin levels is necessary to determine the minimum effective dose.
3. Medication precautions
(1) Fibrosis risk: may cause heart valve disease, pleural effusion, etc., and relevant symptoms need to be evaluated regularly.
(2) Hypotension: Especially when the initial dose is high, orthostatic hypotension is prone to occur, and caution should be exercised when using antihypertensive drugs.
(3) Impulsive control disorder: may result in abnormal behavior such as gambling and hypersexuality, requiring timely reduction or discontinuation of medication.
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