What side effects may occur during the use of Fasturtec enzyme from France?
During the treatment process, Fasturtec may produce various side effects, mainly including allergic reactions, blood system abnormalities, and metabolic disorders. The following will provide a detailed classification of its common and serious side effects, as well as corresponding response measures.
1. Common side effects
During the treatment with Rabelase, the following adverse reactions are common, most of which are mild and can be relieved on their own:
(1) Allergic reactions
About 15% of patients may experience mild allergic symptoms such as rash, itching, and facial flushing. These reactions usually occur within 2 hours after administration and can mostly be controlled by antihistamines.
(2) Abnormal blood system
Including anemia (hemoglobin decrease ≥ 2g/dl), thrombocytopenia, etc., the incidence rate is about 10-20%. These changes are mostly temporary and can be restored after discontinuation of medication.
2. Serious side effects that require immediate medical attention
The following situations indicate the possibility of serious adverse reactions and require immediate medical intervention:
(1) Severe allergic reaction
Symptoms of anaphylactic shock, including dyspnea, laryngeal edema, and hypotension, occur at a rate of approximately 1-2%. These symptoms usually appear quickly after the first dose and require immediate cessation of infusion and emergency measures such as adrenaline.
(2) Hemolytic reaction
G6PD deficiency patients may experience acute hemolysis, manifested as hemoglobinuria, jaundice, and rapid deterioration of renal function. G6PD status must be screened before medication, and positive patients are prohibited from using it.
3. Precautions for special populations
Special attention should be paid to the risk of side effects when using Rabelase in different populations:
(1) Child patients
Children are more prone to fever and vomiting, with an incidence rate 10-15% higher than adults. Close monitoring of body temperature and electrolyte balance is required.
(2) Elderly patients
Patients with renal dysfunction may experience slower drug clearance, which may increase the risk of hematological toxicity. Suggest adjusting the dosage based on creatinine clearance rate.
4. Suggestions for managing side effects
To minimize the impact of side effects, it is recommended to take the following measures:
(1) Preventive medication
Antihistamines and corticosteroids can be used 30 minutes before administration to prevent allergic reactions, with an effective rate of over 80%.
(2) Monitoring plan
During treatment, regular monitoring of blood routine, renal function, and electrolytes is necessary, with special attention paid to changes in uric acid, potassium, phosphorus, and calcium levels.
Disclaimer：《What side effects may occur during the use of Fasturtec enzyme from France?》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！