What is the therapeutic effect of Lasvic from Kyorin Pharmaceutical Co., Ltd. in Japan? Is there anything to pay attention to when patients stop taking medication?
Lasvic, as a broad-spectrum antibacterial drug, has a therapeutic effect closely related to bacterial sensitivity. Discontinuation should be personalized according to the type of infection and clinical response. The following provides a detailed explanation from three aspects: efficacy evaluation, discontinuation criteria, and precautions to ensure the safety and effectiveness of medication.
1. Evaluation of treatment efficacy
(1) Sensitive bacterial infection
The effective rate for respiratory and urinary tract infections caused by gram-negative bacteria (such as Escherichia coli, Klebsiella pneumoniae) and positive bacteria (such as Staphylococcus aureus) can reach 85% -90%.
(2) Drug-resistant bacterial strains
It still maintains moderate activity against some methicillin-resistant Staphylococcus aureus (MRSA) and ESBL producing Enterobacteriaceae bacteria, and should be used in conjunction with drug sensitivity test results.
2. Discontinuation criteria and methods
(1) Conventional treatment course
Mild to moderate infections usually require medication for 7-10 days, and medication should be continued for 48-72 hours after the symptoms have completely disappeared; Complex infections need to be extended to 14 days.
(2) Discontinue medication under special circumstances
When severe allergic reactions (such as rash, difficulty breathing) or symptoms of tendinitis occur, immediate and permanent discontinuation of medication is required, and other antibiotics should be replaced.
3. Precautions for discontinuation of medication
(1) Efficacy confirmation
Before discontinuing medication, it is necessary to recheck inflammatory indicators (such as blood routine, CRP) and imaging to ensure complete clearance of the infection site and avoid recurrence.
(2) Adverse reaction monitoring
Even after discontinuing the medication, it is still necessary to observe for 2-3 days to be alert to the risk of delayed allergic reactions or tendon rupture, especially in elderly and renal insufficiency patients.
(3) Drug interactions
Avoid using preparations containing metal ions within 3 days after discontinuation to prevent residual drugs from forming chelates and affecting absorption.
Disclaimer：《What is the therapeutic effect of Lasvic from Kyorin Pharmaceutical Co., Ltd. in Japan? Is there anything to pay attention to when patients stop taking medication?》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！