Side effects and mitigation methods of Deucravatinib in Ziska, Bangladesh
Deucravatinib, as a novel JAK inhibitor, requires a systematic understanding of its side effect profile and corresponding mitigation measures. The common adverse reactions of this drug involve multiple systems and require differentiated management strategies based on the severity of symptoms. Some severe reactions require immediate medical intervention.
1. Common self relieving side effects
Symptoms such as back pain, constipation, and facial flushing are usually mild, and most gradually adapt with prolonged medication. Maintaining moderate activity and increasing dietary fiber intake can alleviate related symptoms. If it continues to worsen, medical evaluation is necessary.
2. Serious side effects requiring medical intervention
(1) Risk of infection
Possible upper respiratory tract infections, herpes zoster recurrence, etc. During medication, avoid contact with infectious sources and seek medical attention immediately if fever or infection symptoms occur.
(2) Cardiovascular abnormalities
Including arrhythmia, tendency towards thrombosis, etc. Regularly monitor blood pressure and heart rate. If chest pain or lower limb swelling occurs, emergency treatment is required.
(3) Digestive system response
Severe diarrhea or liver dysfunction (jaundice, clay stool) requires immediate discontinuation of medication. During the treatment period, liver enzyme indicators should be tested monthly to avoid alcohol intake.
3. Special organ toxicity management
(1) Skin reaction
When rash or hand foot syndrome (redness, swelling, and scaling) occurs, use non irritating moisturizers. Avoid direct sunlight and seek consultation from a dermatologist if ulcers occur.
(2) Neurological symptoms
Headaches, dizziness, etc. can be adjusted to be administered before bedtime. If seizures or consciousness disorders occur, permanent discontinuation of medication and neurological evaluation are required.
4. Laboratory monitoring requirements
Baseline and every 3 months check blood routine (with a focus on lymphocytes), liver and kidney function, and blood lipids. When there is a decrease in white blood cells, it is necessary to consider suspending medication.
5. Precautions for special populations
Women of childbearing age need to use contraception for one month after discontinuing the medication. Patients over 65 years old need to reduce their weight by 25% and strengthen fall prevention measures.
Disclaimer：《Side effects and mitigation methods of Deucravatinib in Ziska, Bangladesh》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！