Taboo populations, foods, and restrictions of Cenobamate in Angelini, Italy
Cenobamate is an antiepileptic drug, and its use must strictly follow contraindications, food, and restrictions to ensure medication safety and effectiveness. The following content will provide a detailed explanation of relevant taboos and precautions.
1. Taboo population
(1) Pregnant women
Benzodiazepine may cause harm to the fetus, and pregnant women should avoid using it. If necessary, it is necessary to fully evaluate the risks and benefits, and take effective contraceptive measures.
(2) Lactating women
It is not clear whether the medication is secreted through breast milk. Breastfeeding women should weigh the benefits and potential risks of breastfeeding and stop breastfeeding or medication if necessary.
(3) Patients with liver dysfunction
Patients with moderate to severe liver function impairment are contraindicated to use benazepril as it may increase drug exposure and increase the risk of adverse reactions.
(4) Child patients
The safety and efficacy of benazepril in patients under 18 years old have not been established, and it is not recommended for use in children.
2. Forbidden foods
(1) Alcohol
Alcohol may enhance the central nervous system inhibitory effect of benazepril, increase the risk of adverse reactions such as drowsiness and dizziness, and alcohol consumption should be avoided during medication.
(2) Grapefruit and its products
Grapefruit may affect benzoate metabolism by inhibiting CYP3A4 enzyme, leading to an increase in blood drug concentration and an increased risk of adverse reactions.
3. Restrictive conditions
(1) Driving and operating machinery
Benzopheniramate may cause adverse reactions such as drowsiness and dizziness. During medication, driving or operating precision machinery should be avoided until individual reactions are identified.
(2) Drug interactions
The combination of benzodiazepine with strong CYP3A4 inhibitors or inducers may affect efficacy or safety, and should be used with caution and closely monitored.
(3) Renal dysfunction
Patients with mild to moderate renal impairment do not need to adjust the dosage, but adverse reactions need to be closely monitored; Patients with severe renal impairment should be cautious when using it.
Disclaimer：《Taboo populations, foods, and restrictions of Cenobamate in Angelini, Italy》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！