Side effects and relief methods of AstraZeneca version of Tamoxifen
Tamoxifen, as a selective estrogen receptor modulator, commonly has side effects involving the endocrine system, blood system, and reproductive system, which need to be alleviated through regular monitoring and targeted interventions.
1. Common side effects
(1) Endocrine system: hot flashes (about 80%), vaginal dryness/bleeding (35% -40%).
(2) Hematological system: thrombocytopenia (10% -15%), bleeding tendency needs to be monitored.
(3) Reproductive system: Endometrial thickening (17%), postmenopausal women need regular gynecological examinations.
2. Mitigation methods
(1) Hot wave management: Wear breathable clothing, avoid spicy foods/caffeine, and consider non hormonal therapy.
(2) Bleeding prevention: Use a soft bristled toothbrush, avoid vigorous exercise and trauma, and undergo regular blood routine tests.
(3) Gynecological monitoring: Pelvic ultrasound examination every year, abnormal vaginal bleeding requires immediate medical attention.
3. Special precautions
(1) Thrombosis risk: Avoid long-term immobilization during medication, and emergency assessment is necessary for lower limb swelling and pain.
(2) Visual impact: Regular eye examinations, sudden changes in vision require discontinuation of medication and medical attention.
(3) Drug interactions: Avoid using strong CYP2D6 inhibitors (such as fluoxetine) in combination, as it may reduce efficacy.
Disclaimer：《Side effects and relief methods of AstraZeneca version of Tamoxifen》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！