Side effects and mitigation methods of Nebivolol from Macleods Pharmaceuticals in India
Nebivolol, as a selective beta 1 receptor blocker, has side effects mainly involving cardiovascular system, central nervous system, and metabolic abnormalities. Most symptoms are mild and reversible, but caution should be taken for serious reactions such as bradycardia. The following is an explanation from three aspects: common side effect management, serious reactions that require urgent handling, and precautions for special populations.
1. Common side effects and mitigation measures
(1) Headache and dizziness: It is recommended to slowly change position and avoid sudden standing. When symptoms are obvious, the dosage can be reduced and taken in divided doses.
(2) Fatigue and fatigue: It is common in the early stages of medication and usually takes 2-4 weeks to adapt. It is recommended to take a nap in the afternoon and avoid high-intensity exercise.
(3) Gastrointestinal discomfort: Taking with meals can alleviate nausea, and electrolyte solution should be supplemented when diarrhea occurs.
2. Serious reactions requiring immediate medical attention
(1) Bradycardia: If the heart rate is less than 50 beats per minute or accompanied by fainting, medication should be stopped and emergency electrocardiogram monitoring should be performed.
(2) Bronchospasm: Patients with previous asthma who experience wheezing should immediately use bronchodilators.
(3) Depressive symptoms: Psychological intervention is needed when emotions are low and sleep disorders continue to worsen.
3. Special medication precautions
(1) Patients with diabetes: may cover up hypoglycemia symptoms, and the frequency of blood glucose monitoring needs to be strengthened.
(2) Liver and kidney dysfunction: dosage adjustment is required, and regular testing of liver enzymes and creatinine clearance rate is necessary.
(3) Perioperative management: Gradual cessation is required 72 hours before elective surgery to avoid anesthesia synergy.
4. Drug interaction prevention
(1) Avoid using diltiazem in combination: it may increase the risk of bradycardia and conduction block.
(2) Be cautious with NSAIDs: Medications such as ibuprofen may weaken their antihypertensive effect.
(3) Alcohol restriction: may enhance central inhibitory effects, it is recommended to quit drinking during medication.
Disclaimer：《Side effects and mitigation methods of Nebivolol from Macleods Pharmaceuticals in India》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！