Has Epclusa been launched yet? What time do you eat?
The recommended medication time for Epclusa is fixed daily and can be taken on an empty stomach or after a meal, but attention should be paid to the time interval with other medications. Maintaining regular medication can help maintain stable blood drug concentrations and improve treatment effectiveness.
1. Official approval time
(1) In May 2018, it was officially approved by the National Medical Products Administration (NMPA) of China, becoming the first hepatitis C compound preparation in China to cover all genotypes.
2 Commercial supply time
(1) In the third quarter of 2018, the drug import customs clearance and channel distribution were completed, and it was officially sold in the domestic market.
3 Important Subsequent Developments
(1) In 2019, it was included in the reimbursement list through national medical insurance negotiations, with a price reduction of over 85%.
(2) 2020: Update the instruction manual to include medication data for special populations and improve safety information.
4. Regular medication time
(1) Take one tablet once a day, preferably at a fixed time (such as morning or evening) to maintain stable blood drug concentration.
(2) Food has a relatively small impact on drug absorption and can be taken on an empty stomach or after a meal, but a high-fat diet may slightly delay the rate of drug absorption.
5 Special Medication Time Adjustment
(1) When used in combination with proton pump inhibitors, it is necessary to take them every 4 hours to avoid affecting the absorption of Vepatasvir.
(2) If the missed dose does not exceed 18 hours, it should be immediately replenished; If it exceeds 18 hours, skip the current dose and take the medication normally next time. Do not double the dose.
6 Medication precautions
(1) It is recommended to set medication reminders, especially for irregular sleep patterns or travel, to avoid missing medication.
(2) Avoid taking antacids containing aluminum/magnesium for 2 hours before and after medication, and if necessary, leave an interval of at least 4 hours.
(3) Dialysis patients should receive medication after dialysis without adjusting the dosage.
Disclaimer：《Has Epclusa been launched yet? What time do you eat?》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！