Anamorelin usually takes a few years to use
The recommended usage period of Anamorelin is usually no more than 12 weeks (3 months), mainly used for short-term weight management in cancer cachexia patients. Clinical research data indicates that the safety and effectiveness of long-term use have not been established, and periodic evaluations should be strictly followed according to medical advice.
1. Standard treatment course restrictions
(1) Basic course of treatment: The maximum duration of continuous medication under approved indications is 12 weeks, and weight changes and adverse reactions need to be evaluated every 4 weeks.
(2) Extended use: If clinical benefits are significant and well tolerated, intermittent repeated treatment (with an interval of ≥ 4 weeks) may be considered after evaluation by a multidisciplinary team.
Adjustment for Special Groups 2
(1) Elderly patients: For those aged 65 years or older, it is recommended to shorten the initial course of treatment to 8 weeks as the drug clearance rate may decrease.
(2) Liver damage patients: Child Pugh B/C grade should be limited to 4-8 weeks and liver function monitoring should be strengthened.
3 Indications for discontinuation of medication
(1) Stagnation of weight gain: When the weight gain is less than 5% for four consecutive weeks, discontinuation of medication or change of plan should be considered.
(2) Adverse reactions: Immediate termination is required if QT interval prolongation (>500ms), abnormal blood glucose, or grade 3 or above side effects occur.
Disclaimer：《Anamorelin usually takes a few years to use》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！