Medical Information

Axhidrox is a topical anticholinergic preparation. Although its absorption through the skin is limited, some active ingredients can still enter the circulation. Therefore, there is a clear risk for specific populations and high vigilance is required.

1、 Glaucoma patients

Anticholinergic drugs can cause dilated pupils, obstruction of aqueous humor discharge, and induce or worsen acute attacks of angle closure glaucoma, manifested as eye pain, blurred vision, iris, headache, and even nausea and vomiting. Axhidrox should be contraindicated in patients with angle closure glaucoma; Individuals with a history of glaucoma or family history, as well as shallow anterior chamber, must undergo ophthalmic evaluation before use. If eye discomfort occurs during medication, the medication should be stopped immediately and medical attention sought. After applying, be sure to wash your hands and do not allow the medication to come into contact with the eyes.

2、 Urinary retention patients

The anticholinergic effect can weaken the contraction of the bladder detrusor muscle and increase the tension of the urethral sphincter, thereby exacerbating urinary difficulties. Those who have urinary retention, prostatic hyperplasia with dysuria, bladder outlet obstruction should be prohibited or used with caution. Pay attention to urination during medication. If there is difficulty urinating, thinning of the urine stream, lower abdominal pain or inability to urinate, stop taking the medication and seek medical attention in a timely manner. If necessary, catheterization should be performed.

3、 Patients with myasthenia gravis

Patients with myasthenia gravis have impaired neuromuscular transmission, and anticholinergic drugs may interfere with neuromuscular junction function, exacerbate myasthenia symptoms, and even trigger myasthenia crisis, manifested as worsening eyelid ptosis, difficulty swallowing, and difficulty breathing. Axhidrox should be contraindicated for such patients. If the condition requires antiperspirant treatment, alternative options should be selected under joint evaluation by the neurology and dermatology departments.

4、 Other Attention

The above-mentioned population should not use this product on their own; Those who have multiple diseases and are taking other anticholinergic drugs should inform their doctors to avoid cumulative effects. Pregnant women, breastfeeding women, and children should consult a physician before taking medication. If there are changes in vision, difficulty urinating, or worsening muscle weakness after medication, the medication should be stopped immediately and medical attention should be sought.