Precautions for taking Acotamine: Abnormal liver function, diarrhea, and drug interactions
Acotiamide is used for functional dyspepsia. During treatment, attention should be paid to liver function, diarrhea, and drug interactions to ensure safety.
1. Abnormal liver function
1. Assessment before use
Liver function status should be determined before use, and liver function indicators should be checked when necessary.
It is contraindicated in patients with severe hepatic impairment; patients with mild to moderate hepatic impairment must use it cautiously after assessment by a doctor.
2. Monitoring during treatment
Recheck liver function regularly and monitor changes in indicators such as transaminases and bilirubin.
If symptoms such as fatigue, loss of appetite, jaundice, or dark urine occur, seek medical attention promptly.
3. Management principles
If liver function indicators are markedly abnormal, the doctor will assess whether dose reduction, temporary discontinuation, or discontinuation is needed.
Patients must not adjust the dose or stop the drug on their own.
2. Diarrhea
1. Common manifestations
Diarrhea is a relatively common adverse reaction of this product. It is mostly mild and may resolve on its own.
Pay attention to recording the frequency and characteristics of bowel movements and accompanying symptoms.
2. Daily management
Replenish water and electrolytes; oral rehydration salts may be used.
Eat a light diet and avoid cold, raw, greasy, and irritating foods.
3. Indications for medical attention
If frequent watery stools, dehydration, fatigue, dry mouth, etc. occur, seek medical attention promptly.
The doctor will assess whether dose reduction or temporary discontinuation is needed; do not take antidiarrheal drugs on your own to mask symptoms.
3. Drug interactions
1. Inform of all medications
Proactively inform the doctor of prescription drugs, over-the-counter drugs, and health supplements currently being used during visits.
Avoid concomitant use with drugs that affect hepatic enzymes or gastrointestinal motility; the doctor will adjust the regimen when necessary.
2. Note the risks of concomitant medication
When used with other drugs, plasma concentrations may change or adverse reactions may increase.
Strengthen observation during concomitant use and report abnormalities promptly.
3. Avoid adding drugs on your own
Do not add other drugs on your own, especially antidiarrheal drugs, pain relievers, and traditional Chinese medicines.
Any medication adjustment must follow the doctor's instructions.
Disclaimer：《Precautions for taking Acotamine: Abnormal liver function, diarrhea, and drug interactions》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！