Medical Information

Canagliflozin lowers blood glucose by promoting urinary glucose excretion, but it may cause adverse reactions such as urinary tract infections, thirst, and weight loss, which need to be managed scientifically.

I. Prevention and Management of Urinary Tract Infections

1.Common Manifestations

Frequent urination, urgency, and painful urination.

Cloudy or foul-smelling urine.

Lower abdominal discomfort or fever.

2.Preventive Measures

Drink enough water daily, urinate frequently, and do not hold urine.

Keep the perineal area clean and dry.

Avoid excessive use of irritating cleaning products.

3.Management Principles

Seek medical attention promptly if symptoms occur, and undergo urinalysis if necessary.

After diagnosis, use antibacterial drugs as prescribed.

For recurrent infections, evaluate whether to continue the medication.

II. Managing Thirst

1.Causes

Urinary glucose excretion removes water, leading to mild dehydration.

Thirst is more noticeable when blood glucose is high.

2.Management Methods

Drink water in small amounts and frequently, ensuring adequate daily intake.

Avoid sugary drinks; choose plain water or light tea.

Seek medical attention promptly if obvious fatigue or dizziness occurs.

3.Precautions

Do not reduce medication because of fear of thirst.

Patients with heart failure or renal impairment must follow medical advice regarding fluid intake.

III. Management of Weight Loss

1.Causes

Urinary glucose excretion leads to calorie loss.

Some patients experience decreased appetite.

2.Management Methods

Maintain a balanced diet and appropriately increase high-quality protein.

Eat small, frequent meals and avoid excessive dieting.

Monitor weight regularly and record changes.

3.Medical Attention

Seek medical attention if weight drops rapidly or is accompanied by fatigue or nausea.

Rule out weight loss caused by other diseases.

Adjust the medication regimen by a physician if necessary.