Medical Information

Entresto Medication Guide: Take twice a day with meals or on an empty stomach, dose titration and missed dose management

Publisher:海鸥医学顾问     Publication Date:2026-09-18 17:08       The article comes from the Internet      Views:29

Entresto, developed by Novartis, is an innovative drug used for the treatment of chronic heart failure.

1、 Usage and timing of administration

1. Take twice a day, regularly

Entresto usually needs to be taken twice a day (once in the morning and once in the evening) to maintain a stable blood drug concentration in the body.

It is recommended to take medication at roughly the same time every day, such as after breakfast and dinner, which can help develop habits and avoid missed doses.

2. Available with meals or on an empty stomach

Entresto can be taken with food or on an empty stomach.

If you experience stomach discomfort after taking medication, you can choose to take it with meals to alleviate symptoms.

It is important to maintain consistency in the way medication is taken every day. Do not eat with meals today or fast tomorrow to avoid affecting the stability of drug absorption.

3. Swallow the whole piece

Please swallow the entire tablet in warm water, do not break, crush or chew the tablet to avoid affecting its efficacy or increasing the risk of side effects.

2、 Handling of missed services

1. Take it as soon as possible when you remember

If you missed taking it once, remember to take it as soon as possible.

But if the next medication is less than 12 hours away, skip the missed dose and take the next medication according to the original plan.

2. Do not double the dosage

Never take double the dose at once to make up for missed doses, as this may lead to serious consequences such as low blood pressure, dizziness, and even fainting.

3. Record the situation of missed services

If there are frequent missed doses, it is recommended to record the time and reason for the missed doses and inform the doctor during the follow-up visit so that the doctor can evaluate whether adjustments to the plan are needed.

Disclaimer:《Entresto Medication Guide: Take twice a day with meals or on an empty stomach, dose titration and missed dose management》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication!