Precautions for taking anlisentan: hepatotoxicity, peripheral edema, anemia, and drug interactions
Anlishengtan is used to treat pulmonary arterial hypertension. During use, special attention should be paid to hepatotoxicity, peripheral edema, anemia, and drug interactions to ensure medication safety.
1、 Hepatotoxicity
Liver function should be tested before medication.
Regular liver function check ups are required during the treatment period.
Be alert when experiencing fatigue, nausea, jaundice, etc.
Patients with significant liver function abnormalities should discontinue medication and seek medical attention.
Do not increase or decrease the dosage on your own.
People with a history of liver disease should use it with caution.
2、 Peripheral edema
Pay attention to the swelling of the lower limbs and ankles.
Raise your lower limbs appropriately and avoid prolonged standing and sitting.
Limit salt intake and reduce water and sodium retention.
Record weight changes for early detection.
If edema worsens or accompanied by difficulty breathing, seek medical attention promptly.
When necessary, doctors may adjust the dosage or add diuretics.
3、 Anemia
Hemoglobin should be monitored regularly during medication.
Pay attention to symptoms such as fatigue, dizziness, and pale complexion.
Ensure balanced nutrition and supplement iron containing foods appropriately.
Avoid strenuous activities to prevent falls.
When anemia is obvious, medical evaluation is needed.
Adjust the dosage or receive blood transfusion treatment as necessary.
4、 Drug interactions
Avoid co administration with potent inhibitors such as cyclosporine.
Co administration with inducers such as Levofloxacin may reduce therapeutic efficacy.
Be cautious of low blood pressure when used in combination with other antihypertensive drugs.
Avoid taking with grapefruit juice.
When using anticoagulants, the risk of bleeding should be monitored.
Notify the doctor during the consultation that all medications are being taken.
Disclaimer:《Precautions for taking anlisentan: hepatotoxicity, peripheral edema, anemia, and drug interactions》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication!