Medical Information

To ensure medication safety, it is necessary to clarify whether there are serious contraindications before using Allydone transdermal patches. The following two groups of people are strictly prohibited or require extreme caution when using, please carefully compare.

1、 Absolutely prohibited population

Those who are allergic to medicinal adhesives: Those who are known to be allergic to patch backing layers, pressure-sensitive adhesives, or any excipients (such as acrylic esters) are strictly prohibited from using them. Individuals who have previously experienced severe skin rashes, blisters, or systemic allergic reactions (such as difficulty breathing and facial swelling) using other transdermal patches are also prohibited.

2、 Serious illness patients requiring urgent assessment

Severe liver dysfunction: Patients with decompensated cirrhosis, acute liver failure, or Child Pugh C grade severe liver disease are prohibited from using it. This type of population has blocked drug metabolism pathways and is at risk of accumulation.

Severe renal insufficiency: End stage renal disease (estimated glomerular filtration rate eGFR<30mL/min/1.73m ²) or those who have received dialysis treatment are prohibited from using it. Drugs and their metabolites cannot be effectively cleared through the kidneys.

3、 Special Risk Screening and Action Guidelines

Pre medication check items: Before the first application, a recent (within 3 months) liver and kidney function blood test must be completed, and the test report must be presented to the doctor proactively.

Allergy history inquiry: If there has been local redness, swelling, or hardening of adhesive bandages, medical tapes, or any patches, it is necessary to inform the prescribing physician in advance and conduct a skin patch test if necessary.

Taboo alternative: Patients who meet any of the above conditions should not attempt to reduce their dosage, but should request to switch to oral dosage forms or other non patch therapeutic drugs.

4、 Warning and Emergency Handling

If there is widespread skin erosion, worsening skin yellowing, or significant reduction in urine output (<400mL/day) during use, the patch should be immediately removed and the patient should go to the emergency department. Do not wait for routine follow-up appointments.

The above standards are the general safety bottom line, and the specific applicability shall be subject to the final judgment of the attending physician based on the complete medical history and dynamic test results.