Medical Information

As a photosensitizer drug, the side effects of Oxoralen tablets are mainly related to phototoxic reactions, involving multiple systemic reactions in the skin, eyes, and whole body. The following will provide a detailed classification of the various adverse reactions that the drug may cause and corresponding treatment recommendations.

Common side effects of methoxysarin tablets

1. Skin phototoxic reactions

Exposure to ultraviolet radiation after medication may cause sunburn like reactions such as skin burning, erythema, blisters, and in severe cases, skin peeling may occur. Symptoms usually peak 24-48 hours after irradiation and require immediate avoidance of light and cold compress treatment.

2. Eye discomfort

Not wearing goggles may lead to conjunctivitis and keratitis, manifested as eye pain, photophobia, and tearing. Long term excessive exposure may increase the risk of cataracts, and UV resistant glasses must be used during medication.

3. Digestive system reactions

Some patients may experience nausea, vomiting, or discomfort in the upper abdomen. It is recommended to take it with food to alleviate symptoms. Continuous vomiting requires vigilance against dehydration and electrolyte supplementation if necessary.

Serious side effects requiring immediate medical attention

1. Severe skin reactions

If there is bullous dermatitis, skin necrosis, or Stevens Johnson syndrome (characterized by systemic erythema with mucosal ulceration), immediate discontinuation of medication and hospitalization are required.

2. Abnormal liver function

Rare but potentially drug-induced liver injury, characterized by jaundice, darkened urine color, or elevated transaminase levels. During medication, liver function indicators should be regularly monitored.

3. Allergic reactions

Rapid hypersensitivity can manifest as laryngeal edema, difficulty breathing, or decreased blood pressure, requiring immediate adrenaline rescue. Delayed type allergies often present with drug rashes and require treatment with antihistamines.

Potential risks of long-term medication

1. Skin cancer

Long term high-dose phototherapy may increase the risk of squamous cell carcinoma and basal cell carcinoma, especially in patients with albinism. Regular dermatological follow-up examinations are required.

2. Accelerated photoaging

Chronic light exposure can lead to skin elastic fiber degeneration, manifested as deepening wrinkles and pigmentation. Suggest using antioxidant skincare products in combination to slow down the process.

3. Immunosuppression

Repeated phototherapy may lower local skin immunity and increase the risk of infection. Individuals with a history of combined herpes virus infection require prophylactic antiviral treatment.