The side effects and mitigation methods of Lusatrombopag, the Laotian version of Lusatrombopag
The side effects of Lustrombopag can be divided into severe reactions that require immediate medical attention and common discomforts that can be self relieved. Its preventive measures need to be combined with regular monitoring and lifestyle adjustments. The following provides a systematic explanation of the classification of side effects, coping strategies, and special precautions.
1. Serious side effects requiring immediate medical attention
(1) Thrombotic related symptoms: including leg pain/swelling, chest pain, difficulty breathing, or sudden headache, indicating the possibility of venous thromboembolism.
(2) Bleeding manifestations: abnormal gum bleeding, nosebleeds, black stools or subcutaneous bruising, which may be related to abnormal platelet function.
(3) Systemic reactions: high fever accompanied by chills, blurred consciousness, epileptic seizures or sudden visual changes, systemic complications need to be ruled out.
2. Common side effects that can be self relieved
(1) Digestive system: Nausea, decreased appetite, or mild diarrhea, usually subsides within 2-3 days after adaptation, and it is recommended to eat in small portions.
(2) Skin reaction: Light sensitivity or mild rash, need to strengthen sun protection (SPF30+) and avoid direct sunlight.
(3) Nervous system: Transient headaches or dizziness can be relieved by maintaining sufficient rest and avoiding sudden changes in posture.
3. Methods for alleviating side effects
(1) Thrombosis prevention: Patients with restricted mobility should undergo lower limb massage, and high-risk individuals should undergo regular ultrasound screening.
(2) Bleeding management: Use a soft bristled toothbrush to avoid contact with sharp objects. In case of nosebleeds, apply local cold compress for compression.
(3) Digestive discomfort: Take medication after meals, and if necessary, combine proton pump inhibitors to maintain electrolyte balance.
4. Special precautions
(1) Medication monitoring: During the treatment period, platelet count is checked weekly until it stabilizes, and then changed to monthly follow-up.
(2) Drug interactions: Avoid using anticoagulants or NSAIDs in combination, and use them with a 4-hour interval when necessary.
(3) Taboo population: Patients with a history of active thrombosis and Child Pugh Class C liver disease should not use this medication.
Disclaimer：《The side effects and mitigation methods of Lusatrombopag, the Laotian version of Lusatrombopag》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！