What is the usage and dosage of Doptelet? Can special populations eat for a long time?
The usage and dosage of Dovtelet should be personalized according to the indications and patient types, mainly including preoperative platelet elevation for chronic liver disease, treatment of chronic immune thrombocytopenia (ITP) in adults and children, etc. The specific dosage should be dynamically adjusted and strictly monitored in conjunction with platelet count.
Preoperative medication plan for patients with chronic liver disease
(1) Medication should be taken 10-13 days before surgery, with a fixed course of 5 days, once daily with food.
(2) When the platelet count is less than 40 × 10 ⁹/L, 60mg per day. When the platelet count is between 40-50 × 10 ⁹/L, 40mg per day. Surgery should be performed 5-8 days after the last administration.
Usage for 2 adult patients with chronic ITP
(1) The initial dose is 20mg per day, which should be taken with food to maintain a minimum effective dose of ≥ 50 × 10 ⁹/L.
(2) Monitor platelets weekly until stable, then monitor monthly, and continue monitoring for 4 weeks after discontinuation of medication.
Differentiated strategies for 3 pediatric ITP patients
(1) Children aged 6 and above: 20mg tablets per day, with the same usage as adults.
(2) Children aged 1-6: 10mg powder per day, requiring special dosage forms.
4 Dose Adjustment Rules
(1) Platelets<50 × 10 ⁹/lasting for 2 weeks require an increase in dosage, while those>200 × 10 ⁹/liter require a decrease in dosage.
(2) The maximum daily dose for adults is 40mg, and for children it is 20mg. If it is ineffective after 4 weeks, the medication should be discontinued.
5 Principles for Handling Missing Services
(1) If a missed dose is found, it should be taken immediately and the next day according to the original plan. Double dosage is prohibited.
(2) Seek medical attention promptly in case of overdose, as there is no specific antidote available.
Long term medication restrictions for special populations
(1) Pregnant women should weigh the risks to the fetus and refrain from breastfeeding for 28 days after taking medication during lactation.
(2) Individuals with severe liver and kidney dysfunction lack long-term medication data and require careful evaluation.
Disclaimer：《What is the usage and dosage of Doptelet? Can special populations eat for a long time?》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！