The usage, dosage, and special population medication of Tartirelin by Nippon Medical Co., Ltd
The usage and dosage of taltirelin should be adjusted according to the individual situation of the patient, and special attention should be paid to dosage adjustment and contraindications when using it for special populations. The following content provides a detailed explanation of its conventional usage, dosage adjustment principles, and medication precautions for special populations.
1. Usage and dosage
(1) Conventional dosage
The recommended dosage for adults is 0.5mg orally twice a day, and it is recommended to take it at a fixed time to maintain stable blood drug concentration.
(2) Dose adjustment
According to the efficacy and tolerability, it can be gradually increased to twice a day, 1mg each time, with a maximum daily dose not exceeding 2mg.
(3) Administration method
It can be taken before or after meals, but it should be avoided to take it together with calcium, magnesium, or aluminum preparations, as it may affect drug absorption.
2. Medication for special populations
(1) Elderly patients
Starting from low doses (0.25mg per day), gradually increasing according to tolerance, it is necessary to strengthen cardiovascular and neurological monitoring.
(2) Renal insufficiency
Mild to moderate damage (eGFR30-89mL/min) requires a 25% reduction; Severe damage (eGFR<30mL/min) is prohibited.
(3) Liver dysfunction
Child Pugh Class A patients do not require adjustment; Reduce dosage by 50% for B-grade patients; C-grade patients are prohibited from using it.
(4) Pregnant women and lactation period
Pregnant women are prohibited from using it, and women of childbearing age should take reliable contraceptive measures during medication; Breastfeeding women should pause breastfeeding.
(5) Children's medication
The safety and efficacy of using it for patients under 18 years old have not been established and is not recommended.
(6) Other precautions
During the treatment period, it is necessary to regularly evaluate the efficacy and adverse reactions. If severe dizziness or tachycardia occurs, medication should be stopped immediately and medical attention should be sought.
Disclaimer：《The usage, dosage, and special population medication of Tartirelin by Nippon Medical Co., Ltd》Edited and sorted by Seagull Pharmacy's editors. Please contact us in time if there is any infringement. In addition, the suggestions for drug usage, dosage and disease mentioned in the article are only for medical staff's reference, and can not be used as any basis for medication！